For the suit in isolation, the possible lines I would consider are:
(1) Low to the 10, then cash ace. Works against East's xx, xxx, Jxx, Kx, Kxx, KJ, 9, Jxxx, Kxxx.
(2) Low to the queen, then low to the 10. Works against East's xx, xxx, Kx, Kxx, KJx, KJ, J.
(3) Run the queen; if that loses to the king, finesse the 10; if the queen is covered, lead to the 10. Works against East's xx, xxx, J9, J64, Kx, Kxx, 9, J.
(4) Run the queen; if that loses to the king, finesse the 10; if the queen is covered, run the 8. Works against East's 64, xxx, Jx J64, Kx, Kxx, 6, 9, J.
(5) Run the 8; if that loses to the jack or king, finesse the 10; otherwise cash the ace. Works against East's 64, xxx, J6, J4, Jxx, K9, Kxx, 6, K. (I've assumed that when the cards are 9xx-KJ, West will play the nine on the second round.)
(1) appears to be the best of those. Compared to (2), it scores equally well on the 3-2 breaks, but gains against more 4-1s. I find that a bit surprising. Have I missed something?
Edit:
(6) Cash the ace and lead to the queen (ewj's suggestion). Works against East's xxx, Jx, Kx, Kxx, KJ, KJx, K (but not J, assuming they'd also play J from J9).
(7) Cash the ace and lead to the queen, except if West plays the nine on the first round, in which case we run the 10. As good as (6) on the 3-2s, but also picks up KJ64.
I think (7) is still one 4-1 break worse than (1).
This post has been edited by gnasher: 2009-February-15, 11:51
1♠ P 2♦ P
3♣ P 3♠ P
4♣ P 4NT P
5♠ P 6♠ all pass