After East passes, most South's will pass. Some might have a gadget showing a 5-4 major/minor preempt, but even then, 5422 hands are known not to play very well. North now opens 1♣ (if playing natural) and South either bids 1♥ or 2♥. If you play strong jump shifts or weak jump shifts over a minor, you may want to consider what you play as a passed hand jump bids over a minor. I believe that a fit jump is quite a useful use for this bid and was found at one table. Another table commented that they would have fit jumped, but the hand wasn't good enough. For those that play reverse flannery, I'm not sure if it's best to keep with reverse flannery after passing or not. I just haven't played the convention enough, since I've been entrenched in a strong diamond system for so long.
Anyway, typically after North opens 1♣, South will bid 1♥ and then North will reverse into 2♦. Here there need to be some agreements. For example, I normally play the cheaper of fourth suit and 2NT as a lebensohl-like bid, showing a minimum for my bidding thus far. I'm sure others will play differently. I believe South should show his clubs and be willing to force to game. Whether North decides to contract for 3NT or 5♣ is another matter.
Over a strong club auction, South has to start with either a negative or semi-positive. But, I will let the strong-clubbers describe the rest to you.

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